{"id":343,"date":"2026-07-09T21:22:53","date_gmt":"2026-07-09T12:22:53","guid":{"rendered":"https:\/\/kurashinokusuribako.com\/?p=343"},"modified":"2026-07-09T21:22:53","modified_gmt":"2026-07-09T12:22:53","slug":"%e3%80%90%e8%96%ac%e5%89%a4%e5%b8%ab%e3%81%8c%e8%a7%a3%e8%aa%ac%e3%80%91nsaids%e5%87%a6%e6%96%b9%e6%99%82%e3%81%ab%e3%83%ac%e3%83%90%e3%83%9f%e3%83%94%e3%83%89%e3%81%a0%e3%81%91%e3%81%a7%e3%81%af","status":"publish","type":"post","link":"https:\/\/kurashinokusuribako.com\/?p=343","title":{"rendered":"\u3010\u85ac\u5264\u5e2b\u304c\u89e3\u8aac\u3011NSAIDs\u51e6\u65b9\u6642\u306b\u30ec\u30d0\u30df\u30d4\u30c9\u3060\u3051\u3067\u306f\u4e0d\u5341\u5206\uff1fPPI\u3068\u306e\u9055\u3044\u3092\u89e3\u8aac"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">NSAIDs\uff08\u30ed\u30ad\u30bd\u30cb\u30f3\u00ae\u3084\u30bb\u30ec\u30b3\u30c3\u30af\u30b9\u00ae\u306a\u3069\uff09\u3092\u51e6\u65b9\u3055\u308c\u308b\u969b\u3001\u300c\u30ec\u30d0\u30df\u30d4\u30c9\uff08\u30e0\u30b3\u30b9\u30bf\u00ae\uff09\u300d\u304c\u4e00\u7dd2\u306b\u51e6\u65b9\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3088\u306d\uff1f<br>\u81ea\u5206\u3082\u6295\u85ac\u306e\u969b\u306b\u306f\u300c\u75db\u307f\u6b62\u3081\u306f\u80c3\u3092\u8352\u3089\u3059\u3053\u3068\u304c\u3042\u308b\u306e\u3067\u3001\u80c3\u85ac\u3082\u4e00\u7dd2\u306b\u51e6\u65b9\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u300d\u306a\u3069\u3068\u60a3\u8005\u3055\u3093\u306b\u8aac\u660e\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u5c11\u3057\u524d\u306bX\uff08\u65e7Twitter\uff09\u3067\u3082\u8a71\u984c\uff1f\u306b\u306a\u3063\u3066\u3044\u305f\u3088\u3046\u306b\u3001<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u30ec\u30d0\u30df\u30d4\u30c9\u3060\u3051\u3067\u80c3\u6f70\u760d\u306f\u4e88\u9632\u3067\u304d\u308b\u306e\uff1f<\/li>\n\n\n\n<li>PPI\uff08\u30e9\u30f3\u30bd\u30d7\u30e9\u30be\u30fc\u30eb\u306a\u3069\uff09\u3068\u4f55\u304c\u9055\u3046\u306e\uff1f<\/li>\n\n\n\n<li>\u306a\u305c\u4eba\u306b\u3088\u3063\u3066\u51e6\u65b9\u3055\u308c\u308b\u80c3\u85ac\u304c\u9055\u3046\u306e\uff1f<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u3068\u7591\u554f\u306b\u601d\u3063\u305f\u3053\u3068\u306f\u3042\u308a\u307e\u305b\u3093\u304b\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u3053\u3067\u4eca\u56de\u306f\u3001NSAIDs\u306b\u3088\u308b\u80c3\u969c\u5bb3\u306e\u4e88\u9632\u306b\u304a\u3051\u308b\u30ec\u30d0\u30df\u30d4\u30c9\u306e\u5f79\u5272\u3068\u3001\u5358\u72ec\u3067\u306f\u4e0d\u5341\u5206\u3068\u306a\u308b\u30b1\u30fc\u30b9\u306b\u3064\u3044\u3066\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3084\u8ad6\u6587\u3092\u3082\u3068\u306b\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h1 class=\"wp-block-heading\">NSAIDs\u306f\u306a\u305c\u80c3\u3092\u8352\u3089\u3059\u306e\uff1f<\/h1>\n\n\n\n<p class=\"wp-block-paragraph\">NSAIDs\u306f\u3001\u75db\u307f\u3084\u708e\u75c7\u306e\u539f\u56e0\u3068\u306a\u308b\u300c<span class=\"swl-marker mark_yellow\"><strong>\u30d7\u30ed\u30b9\u30bf\u30b0\u30e9\u30f3\u30b8\u30f3\uff08PG<\/strong>\uff09<\/span>\u300d\u3068\u3044\u3046\u7269\u8cea\u306e\u7523\u751f\u3092\u6291\u3048\u308b\u3053\u3068\u3067\u52b9\u679c\u3092\u767a\u63ee\u3057\u307e\u3059\u3002<br>\u3057\u304b\u3057\u3001\u30d7\u30ed\u30b9\u30bf\u30b0\u30e9\u30f3\u30b8\u30f3\u306b\u306f\u80c3\u7c98\u819c\u306e\u9632\u5fa1\u306b\u3082\u91cd\u8981\u306a\u5f79\u5272\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30d7\u30ed\u30b9\u30bf\u30b0\u30e9\u30f3\u30b8\u30f3\u306b\u3088\u308b\u52b9\u679c\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3059\u3002<\/p>\n\n\n\n<div class=\"wp-block-group is-style-big_icon_good\"><div class=\"wp-block-group__inner-container\">\n<ul class=\"wp-block-list\">\n<li>\u80c3\u7c98\u6db2\u3092\u5206\u6ccc\u3059\u308b<\/li>\n\n\n\n<li>\u80c3\u306e\u8840\u6d41\u3092\u4fdd\u3064<\/li>\n\n\n\n<li>\u80c3\u7c98\u819c\u306e\u4fee\u5fa9\u3092\u4fc3\u3059<\/li>\n\n\n\n<li>\u91cd\u70ad\u9178\u3092\u5206\u6ccc\u3057\u3066\u80c3\u9178\u3092\u4e2d\u548c\u3059\u308b<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">NSAIDs\u306b\u3088\u3063\u3066\u30d7\u30ed\u30b9\u30bf\u30b0\u30e9\u30f3\u30b8\u30f3\u304c\u6e1b\u5c11\u3059\u308b\u3068\u3001\u80c3\u7c98\u6db2\u3084\u91cd\u70ad\u9178\u5206\u6ccc\u3001\u80c3\u7c98\u819c\u8840\u6d41\u3001\u7c98\u819c\u4fee\u5fa9\u80fd\u304c\u4f4e\u4e0b\u3057\u3001\u80c3\u9178\u306b\u3088\u308b\u969c\u5bb3\u3092\u53d7\u3051\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002\u305d\u306e\u7d50\u679c\u3001\u80c3\u708e\u3084\u80c3\u6f70\u760d\u3001\u5341\u4e8c\u6307\u8178\u6f70\u760d\u3001\u3055\u3089\u306b\u306f\u6d88\u5316\u7ba1\u51fa\u8840\u306e\u30ea\u30b9\u30af\u304c\u4e0a\u6607\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">NSAIDs\u306b\u3088\u3063\u3066\u30d7\u30ed\u30b9\u30bf\u30b0\u30e9\u30f3\u30b8\u30f3\u304c\u6e1b\u5c11\u3059\u308b\u3068\u3001\u80c3\u306e\u9632\u5fa1\u6a5f\u80fd\u304c\u4f4e\u4e0b\u3057\u3001\u80c3\u9178\u306b\u3088\u308b\u30c0\u30e1\u30fc\u30b8\u3092\u53d7\u3051\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"962\" height=\"1024\" data-src=\"https:\/\/kurashinokusuribako.com\/wp-content\/uploads\/2026\/07\/PG\u4f5c\u7528\u6a5f\u5e8f-962x1024.png\" alt=\"\" class=\"wp-image-348 lazyload\" data-srcset=\"https:\/\/kurashinokusuribako.com\/wp-content\/uploads\/2026\/07\/PG\u4f5c\u7528\u6a5f\u5e8f-962x1024.png 962w, https:\/\/kurashinokusuribako.com\/wp-content\/uploads\/2026\/07\/PG\u4f5c\u7528\u6a5f\u5e8f-282x300.png 282w, https:\/\/kurashinokusuribako.com\/wp-content\/uploads\/2026\/07\/PG\u4f5c\u7528\u6a5f\u5e8f-768x817.png 768w, https:\/\/kurashinokusuribako.com\/wp-content\/uploads\/2026\/07\/PG\u4f5c\u7528\u6a5f\u5e8f.png 1216w\" data-sizes=\"(max-width: 962px) 100vw, 962px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 962px; --smush-placeholder-aspect-ratio: 962\/1024;\" \/><\/figure>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h1 class=\"wp-block-heading\">\u30ec\u30d0\u30df\u30d4\u30c9\u306f\u3069\u306e\u3088\u3046\u306a\u80c3\u85ac\uff1f<\/h1>\n\n\n\n<p class=\"wp-block-paragraph\">\u30ec\u30d0\u30df\u30d4\u30c9\u306f\u300c<strong><span class=\"swl-marker mark_yellow\">\u80c3\u7c98\u819c\u4fdd\u8b77\u85ac<\/span><\/strong>\u300d\u306b\u5206\u985e\u3055\u308c\u308b\u85ac\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u80c3\u9178\u3092\u6291\u3048\u308b\u85ac\u3067\u306f\u306a\u304f\u3001<strong><span class=\"swl-marker mark_yellow\">\u80c3\u304c\u672c\u6765\u6301\u3063\u3066\u3044\u308b\u9632\u5fa1\u6a5f\u80fd\u3092\u9ad8\u3081\u308b<\/span><\/strong>\u3053\u3068\u3067\u80c3\u7c98\u819c\u3092\u5b88\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e3b\u306a\u4f5c\u7528\u306f\u6b21\u306e\u3068\u304a\u308a\u3067\u3059\u3002<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<h4 class=\"wp-block-heading\">18. \u85ac\u52b9\u85ac\u7406<\/h4>\n\n\n\n<h5 class=\"wp-block-heading\">18.1\u3000\u4f5c\u7528\u6a5f\u5e8f<\/h5>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>18.1.1\u3000\u80c3\u7c98\u819c\u4fdd\u8b77\u3001\u640d\u50b7\u6cbb\u7652\u4fc3\u9032\u4f5c\u7528<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30ec\u30d0\u30df\u30d4\u30c9\u306f\u3001\u5185\u56e0\u6027\u30d7\u30ed\u30b9\u30bf\u30b0\u30e9\u30f3\u30b8\u30f3\u5897\u52a0\u3084\u80c3\u7c98\u6db2\u91cf\u5897\u52a0\u306a\u3069\u306b\u3088\u308b\u80c3\u7c98\u819c\u4fdd\u8b77\u4f5c\u7528\u3001\u640d\u50b7\u80c3\u7c98\u819c\u306e\u6cbb\u7652\u4fc3\u9032\u4f5c\u7528\u304c\u8a8d\u3081\u3089\u308c\u3066\u3044\u308b\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>18.1.2\u3000\u80c3\u7c98\u819c\u306e\u708e\u75c7\u6291\u5236\u4f5c\u7528<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30ec\u30d0\u30df\u30d4\u30c9\u306f\u3001\u30d5\u30ea\u30fc\u30e9\u30b8\u30ab\u30eb\u6291\u5236\u3084\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u7523\u751f\u6291\u5236\u306a\u3069\u306b\u3088\u308a\u80c3\u7c98\u819c\u306e\u708e\u75c7\u3092\u6291\u5236\u3059\u308b\u4f5c\u7528\u304c\u8a8d\u3081\u3089\u308c\u3066\u3044\u308b\u3002<br><a href=\"https:\/\/www.kegg.jp\/medicus-bin\/japic_med?japic_code=00065918\">\u533b\u7642\u7528\u533b\u85ac\u54c1 : \u30ec\u30d0\u30df\u30d4\u30c9<\/a>\u3088\u308a\u5f15\u7528<\/p>\n<\/blockquote>\n\n\n\n<p class=\"wp-block-paragraph\">\u7c21\u5358\u306b\u8a00\u3046\u3068\u3001\u30ec\u30d0\u30df\u30d4\u30c9\u306f\u300c\u5f31\u304f\u306a\u3063\u305f\u80c3\u7c98\u819c\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u85ac\u300d\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u4e00\u65b9\u3067\u3001\u80c3\u9178\u306e\u5206\u6ccc\u3092\u6291\u3048\u308b\u4f5c\u7528\u306f\u307b\u3068\u3093\u3069\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h1 class=\"wp-block-heading\">\u30ec\u30d0\u30df\u30d4\u30c9\u306f\u52b9\u679c\u304c\u306a\u3044\u85ac\u3067\u306f\u306a\u3044<\/h1>\n\n\n\n<p class=\"wp-block-paragraph\">\u300c\u30ec\u30d0\u30df\u30d4\u30c9\u306f\u610f\u5473\u304c\u306a\u3044\u300d\u3068\u3044\u3046\u610f\u898b\u3092\u898b\u304b\u3051\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u305d\u308c\u306f\u6b63\u78ba\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8907\u6570\u306e\u81e8\u5e8a\u8a66\u9a13\u3092\u307e\u3068\u3081\u305f\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3067\u306f\u3001\u30ec\u30d0\u30df\u30d4\u30c9\u306f\u30d7\u30e9\u30bb\u30dc\uff08\u507d\u85ac\uff09\u3068\u6bd4\u8f03\u3057\u3066\u3001NSAIDs\u306b\u3088\u308b\u80c3\u30fb\u5341\u4e8c\u6307\u8178\u7c98\u819c\u969c\u5bb3\u3092\u6e1b\u5c11\u3055\u305b\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"wp-block-group is-style-big_icon_good\"><div class=\"wp-block-group__inner-container\">\n<ul class=\"wp-block-list\">\n<li>2013\u5e74\u306e\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u30fb\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3067\u306f\u300115\u4ef6\u306eRCT\uff08965\u4f8b\uff09\u304c\u89e3\u6790\u3055\u308c\u3001\u30ec\u30d0\u30df\u30d4\u30c9\u306f\u30d7\u30e9\u30bb\u30dc\u3068\u6bd4\u8f03\u3057\u3066NSAIDs\u306b\u3088\u308b\u80c3\u30fb\u5341\u4e8c\u6307\u8178\u7c98\u819c\u969c\u5bb3\u3092\u6709\u610f\u306b\u6e1b\u5c11\u3055\u305b\u305f\u3002<br>PubMed\uff1a<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23456504\/\">Rebamipide helps defend against nonsteroidal anti-inflammatory drugs induced gastroenteropathy: a systematic review and meta-analysis<\/a><\/li>\n\n\n\n<li>\u3055\u3089\u306b2025\u5e74\u767a\u8868\uff082026\u5e74\u8a8c\u9762\u63b2\u8f09\uff09\u306e\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3067\u3082\u300113\u8a66\u9a13\u306e\u7d71\u5408\u89e3\u6790\u3067\u3001\u30ec\u30d0\u30df\u30d4\u30c9\u306f\u30d7\u30e9\u30bb\u30dc\u3068\u6bd4\u8f03\u3057\u3066\u6d88\u5316\u7ba1\u7c98\u819c\u969c\u5bb3\u3092\u6709\u610f\u306b\u6e1b\u5c11\u3055\u305b\u305f\u3002<br>PubMed\uff1a<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40366001\/\">Efficacy of Rebamipide in the Prevention of Nonsteroidal Anti-Inflammatory Drug-Induced Gastrointestinal Mucosal Breaks: A Systematic Review and Meta-Analysis<\/a><\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">\u3064\u307e\u308a\u3001<strong>\u30ec\u30d0\u30df\u30d4\u30c9\u306b\u306f<span class=\"swl-marker mark_yellow\">\u4e00\u5b9a\u306e\u4e88\u9632\u52b9\u679c<\/span>\u304c\u3042\u308b<\/strong>\u3068\u3044\u3046\u3053\u3068\u3067\u3059<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3067\u306f\u3001\u306a\u305c\u300c\u30ec\u30d0\u30df\u30d4\u30c9\u3060\u3051\u3067\u306f\u4e0d\u5341\u5206\u300d\u3068\u8a00\u308f\u308c\u308b\u3053\u3068\u304c\u3042\u308b\u306e\u3067\u3057\u3087\u3046\u304b\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h1 class=\"wp-block-heading\">\u30ec\u30d0\u30df\u30d4\u30c9\u5358\u72ec\u3067\u306f\u4e0d\u5341\u5206\u3068\u306a\u308b3\u3064\u306e\u7406\u7531<\/h1>\n\n\n\n<h2 class=\"wp-block-heading\">\u7406\u7531\u2460 \u80c3\u9178\u305d\u306e\u3082\u306e\u306f\u6291\u3048\u3089\u308c\u306a\u3044<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">NSAIDs\u306b\u3088\u3063\u3066\u80c3\u7c98\u819c\u306e<strong><span class=\"swl-marker mark_yellow\">\u9632\u5fa1\u529b\u306f\u4f4e\u4e0b<\/span><\/strong>\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u72b6\u614b\u3067\u80c3\u9178\u304c\u5206\u6ccc\u3055\u308c\u7d9a\u3051\u308b\u3068\u3001\u7c98\u819c\u306f\u3055\u3089\u306b\u50b7\u3064\u304d\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30ec\u30d0\u30df\u30d4\u30c9\u306f\u80c3\u7c98\u819c\u3092\u4fdd\u8b77\u3057\u307e\u3059\u304c\u3001\u80c3\u9178\u306e\u5206\u6ccc\u91cf\u3092\u6e1b\u3089\u3059\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3001PPI\u3084P-CAB\u306f\u80c3\u9178\u306e\u5206\u6ccc\u3092\u5f37\u529b\u306b\u6291\u5236\u3059\u308b\u305f\u3081\u3001\u80c3\u7c98\u819c\u3078\u306e\u30c0\u30e1\u30fc\u30b8\u305d\u306e\u3082\u306e\u3092\u6e1b\u3089\u3059\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3064\u307e\u308a<\/p>\n\n\n\n<div class=\"wp-block-group is-style-big_icon_good\"><div class=\"wp-block-group__inner-container\">\n<ul class=\"wp-block-list\">\n<li>\u30ec\u30d0\u30df\u30d4\u30c9\uff1a\u9632\u5fa1\u56e0\u5b50\u3092\u5897\u3084\u3059<\/li>\n\n\n\n<li>PPI\u30fbP-CAB\uff1a\u653b\u6483\u56e0\u5b50\uff08\u80c3\u9178\uff09\u3092\u6e1b\u3089\u3059<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">\u3068\u3044\u3046\u9055\u3044\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"398\" data-src=\"https:\/\/kurashinokusuribako.com\/wp-content\/uploads\/2026\/07\/PPI\u6bd4\u8f03-1024x398.png\" alt=\"\" class=\"wp-image-349 lazyload\" data-srcset=\"https:\/\/kurashinokusuribako.com\/wp-content\/uploads\/2026\/07\/PPI\u6bd4\u8f03-1024x398.png 1024w, https:\/\/kurashinokusuribako.com\/wp-content\/uploads\/2026\/07\/PPI\u6bd4\u8f03-300x117.png 300w, https:\/\/kurashinokusuribako.com\/wp-content\/uploads\/2026\/07\/PPI\u6bd4\u8f03-768x299.png 768w, https:\/\/kurashinokusuribako.com\/wp-content\/uploads\/2026\/07\/PPI\u6bd4\u8f03.png 1536w\" data-sizes=\"(max-width: 1024px) 100vw, 1024px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 1024px; --smush-placeholder-aspect-ratio: 1024\/398;\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">\u7406\u7531\u2461 \u9ad8\u30ea\u30b9\u30af\u60a3\u8005\u3067\u306fPPI\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u308b<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">NSAIDs\u3092\u670d\u7528\u3059\u308b\u4eba\u3059\u3079\u3066\u304c\u540c\u3058\u30ea\u30b9\u30af\u3068\u3044\u3046\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6b21\u306e\u3088\u3046\u306a\u65b9\u306f\u3001\u80c3\u6f70\u760d\u3084\u6d88\u5316\u7ba1\u51fa\u8840\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"wp-block-group is-style-big_icon_good\"><div class=\"wp-block-group__inner-container\">\n<ul class=\"wp-block-list\">\n<li>65\u6b73\u4ee5\u4e0a\u306e\u9ad8\u9f62\u8005<\/li>\n\n\n\n<li>\u80c3\u6f70\u760d\u30fb\u5341\u4e8c\u6307\u8178\u6f70\u760d\u306e\u65e2\u5f80\u304c\u3042\u308b<\/li>\n\n\n\n<li>\u6297\u8840\u6813\u85ac\u3092\u670d\u7528\u3057\u3066\u3044\u308b<\/li>\n\n\n\n<li>\u30b9\u30c6\u30ed\u30a4\u30c9\u3092\u670d\u7528\u3057\u3066\u3044\u308b<\/li>\n\n\n\n<li>NSAIDs\u3092\u9577\u671f\u9593\u670d\u7528\u3059\u308b<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u3088\u3046\u306a\u60a3\u8005\u3055\u3093\u3067\u306f\u30ec\u30d0\u30df\u30d4\u30c9\u306b\u3088\u308b\u52b9\u679c\u3060\u3051\u306f\u4e0d\u5341\u5206\u306a\u3053\u3068\u304c\u591a\u304f\u3001\u56fd\u5185\u5916\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u3082PPI\u306b\u3088\u308b<strong><span class=\"swl-marker mark_yellow\">\u4e88\u9632\u304c\u63a8\u5968<\/span><\/strong>\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u7406\u7531\u2462 PPI\u306e\u65b9\u304c\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u8c4a\u5bcc<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u30ec\u30d0\u30df\u30d4\u30c9\u306b\u3082\u4e00\u5b9a\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306f\u3042\u308a\u307e\u3059\u304c\u3001PPI\u306f\u3055\u3089\u306b\u591a\u304f\u306e\u81e8\u5e8a\u8a66\u9a13\uff08RCT\uff09\u304c\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u73fe\u5728\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u3082\u3001<\/p>\n\n\n\n<div class=\"wp-block-group is-style-big_icon_good\"><div class=\"wp-block-group__inner-container\">\n<ul class=\"wp-block-list\">\n<li><strong>\u6f70\u760d\u4e88\u9632\u52b9\u679c<\/strong><\/li>\n\n\n\n<li><strong>\u6d88\u5316\u7ba1\u51fa\u8840\u4e88\u9632<\/strong><\/li>\n\n\n\n<li><strong>\u518d\u767a\u4e88\u9632<\/strong><\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">\u306b\u3064\u3044\u3066\u3001\u591a\u304f\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u84c4\u7a4d\u3055\u308c\u3066\u3044\u308b\u306e\u306fPPI\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u305f\u3081\u3001\u9ad8\u30ea\u30b9\u30af\u60a3\u8005\u3067\u306fPPI\u304c\u7b2c\u4e00\u9078\u629e\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h1 class=\"wp-block-heading\">\u30ec\u30d0\u30df\u30d4\u30c9\u3060\u3051\u3067\u5341\u5206\u306a\u5834\u5408\u3082\u3042\u308b<\/h1>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u3053\u307e\u3067\u8aad\u3080\u3068\u3001\u300c\u30ec\u30d0\u30df\u30d4\u30c9\u306f\u4f7f\u3046\u610f\u5473\u304c\u306a\u3044\u306e\u3067\u306f\uff1f\u300d\u3068\u601d\u308f\u308c\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u3001\u305d\u3046\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4f8b\u3048\u3070\u3001<\/p>\n\n\n\n<div class=\"wp-block-group is-style-big_icon_good\"><div class=\"wp-block-group__inner-container\">\n<ul class=\"wp-block-list\">\n<li>\u82e5\u3044\u4eba<\/li>\n\n\n\n<li>NSAIDs\u3092\u6570\u65e5\u3060\u3051\u4f7f\u7528\u3059\u308b<\/li>\n\n\n\n<li>\u80c3\u6f70\u760d\u306e\u65e2\u5f80\u304c\u306a\u3044<\/li>\n\n\n\n<li>\u4ed6\u306b\u30ea\u30b9\u30af\u56e0\u5b50\u304c\u306a\u3044<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">\u3068\u3044\u3063\u305f\u4f4e\u30ea\u30b9\u30af\u60a3\u8005\u3067\u306f\u3001\u30ec\u30d0\u30df\u30d4\u30c9\u306e\u307f\u304c\u51e6\u65b9\u3055\u308c\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u80c3\u85ac\u306f\u300c\u8ab0\u306b\u3067\u3082\u540c\u3058\u3082\u306e\u3092\u4f7f\u3046\u300d\u306e\u3067\u306f\u306a\u304f\u3001\u60a3\u8005\u3055\u3093\u3054\u3068\u306e\u30ea\u30b9\u30af\u306b\u5fdc\u3058\u3066\u9078\u629e\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h1 class=\"wp-block-heading\">\u85ac\u5264\u5e2b\u304c\u51e6\u65b9\u305b\u3093\u3067\u78ba\u8a8d\u3057\u3066\u3044\u308b\u30dd\u30a4\u30f3\u30c8<\/h1>\n\n\n\n<p class=\"wp-block-paragraph\">\u85ac\u5264\u5e2b\u306f\u3001NSAIDs\u3068\u80c3\u85ac\u304c\u51e6\u65b9\u3055\u308c\u3066\u3044\u308b\u5834\u5408\u3001\u6b21\u306e\u3088\u3046\u306a\u70b9\u3092\u78ba\u8a8d\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"wp-block-group is-style-big_icon_good\"><div class=\"wp-block-group__inner-container\">\n<ul class=\"wp-block-list\">\n<li>NSAIDs\u306f\u77ed\u671f\u9593\u304b\u9577\u671f\u9593\u304b<\/li>\n\n\n\n<li>\u60a3\u8005\u3055\u3093\u306e\u5e74\u9f62<\/li>\n\n\n\n<li>\u80c3\u6f70\u760d\u306e\u65e2\u5f80\u306f\u3042\u308b\u304b<\/li>\n\n\n\n<li>\u6297\u8840\u6813\u85ac\u3084\u30b9\u30c6\u30ed\u30a4\u30c9\u3092\u4f75\u7528\u3057\u3066\u3044\u306a\u3044\u304b<\/li>\n\n\n\n<li>\u814e\u6a5f\u80fd\u3084\u809d\u6a5f\u80fd\u306b\u554f\u984c\u306f\u306a\u3044\u304b<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u3089\u3092\u7dcf\u5408\u7684\u306b\u5224\u65ad\u3057\u3001\u300c\u3053\u306e\u60a3\u8005\u3055\u3093\u306b\u306f\u30ec\u30d0\u30df\u30d4\u30c9\u3067\u5341\u5206\u304b\u300d\u300cPPI\u3092\u63d0\u6848\u3057\u305f\u65b9\u304c\u3088\u3044\u304b\u300d\u3092\u8003\u3048\u306a\u304c\u3089\u8abf\u5264\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u306bPPI\u306f\u809d\u4ee3\u8b1d\u3067\u3042\u308a\u3001\u809d\u6a5f\u80fd\u969c\u5bb3\u306e\u60a3\u8005\u3055\u3093\u304c\u9577\u671f\u670d\u7528\u3057\u305f\u7d50\u679c\u526f\u4f5c\u7528\u304c\u767a\u73fe\u3057\u305f\u306a\u3069\u306e\u5831\u544a\u304c\u5b9a\u671f\u7684\u306b\u76ee\u306b\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h1 class=\"wp-block-heading\">\u307e\u3068\u3081<\/h1>\n\n\n\n<p class=\"wp-block-paragraph\">NSAIDs\u306b\u3088\u308b\u80c3\u969c\u5bb3\u3092\u4e88\u9632\u3059\u308b\u305f\u3081\u306b\u51e6\u65b9\u3055\u308c\u308b\u30ec\u30d0\u30df\u30d4\u30c9\u306f\u3001\u300c<span class=\"swl-marker mark_yellow\"><strong>\u52b9\u679c\u304c\u306a\u3044\u85ac<\/strong><\/span>\u300d\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u80c3\u7c98\u819c\u306e\u9632\u5fa1\u6a5f\u80fd\u3092\u9ad8\u3081\u308b\u3053\u3068\u3067\u3001NSAIDs\u306b\u3088\u308b\u80c3\u7c98\u819c\u969c\u5bb3\u3092\u8efd\u6e1b\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3067\u3001\u80c3\u9178\u306e\u5206\u6ccc\u3092\u6291\u3048\u308b\u4f5c\u7528\u306f\u306a\u3044\u305f\u3081\u3001\u80c3\u6f70\u760d\u3084\u6d88\u5316\u7ba1\u51fa\u8840\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u60a3\u8005\u3055\u3093\u3067\u306f\u3001PPI\u3084P-CAB\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5927\u5207\u306a\u306e\u306f\u3001\u300c\u30ec\u30d0\u30df\u30d4\u30c9\u304bPPI\u304b\u300d\u3068\u3044\u3046\u4e8c\u8005\u629e\u4e00\u3067\u306f\u306a\u304f\u3001\u60a3\u8005\u3055\u3093\u4e00\u4eba\u3072\u3068\u308a\u306e\u30ea\u30b9\u30af\u306b\u5fdc\u3058\u3066\u9069\u5207\u306a\u80c3\u85ac\u3092\u9078\u3076\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3082\u3057NSAIDs\u3092\u9577\u671f\u9593\u670d\u7528\u3059\u308b\u4e88\u5b9a\u304c\u3042\u308b\u65b9\u3084\u3001\u904e\u53bb\u306b\u80c3\u6f70\u760d\u3092\u7d4c\u9a13\u3057\u305f\u3053\u3068\u304c\u3042\u308b\u65b9\u306f\u3001\u81ea\u5df1\u5224\u65ad\u305b\u305a\u3001\u533b\u5e2b\u3084\u85ac\u5264\u5e2b\u306b\u76f8\u8ac7\u3059\u308b\u3088\u3046\u306b\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h1 class=\"wp-block-heading\">\u53c2\u8003\u6587\u732e<\/h1>\n\n\n\n<p class=\"wp-block-paragraph\">\u30fb<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33620586\/\">Evidence-based clinical practice guidelines for peptic ulcer disease 2020<\/a><br><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23456504\/\">\u30fbRebamipide helps defend against nonsteroidal anti-inflammatory drugs induced gastroenteropathy: a systematic review and meta-analysis<\/a><br>\u30fb<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40366001\/?utm_source=chatgpt.com\">Efficacy of Rebamipide in the Prevention of NSAID-Induced Gastrointestinal Mucosal Breaks: A Systematic Review and Meta-Analysis<\/a><br>\u30fb<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41599742\/?utm_source=chatgpt.com\">Rebamipide as an Adjunctive Therapy for Gastrointestinal Diseases: An Umbrella Review<\/a><br>\u30fb<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18188417\/\">Comparison of rebamipide and misoprostol in preventing NSAID-induced gastropathy (STORM Study)<\/a><br>\u30fb<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19240698\/\">Guidelines for Prevention of NSAID-Related Ulcer Complications<\/a><br>\u30fb<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18321440\/\">Prevention of NSAID-induced gastroduodenal ulcers<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>NSAIDs\uff08\u30ed\u30ad\u30bd\u30cb\u30f3\u00ae\u3084\u30bb\u30ec\u30b3\u30c3\u30af\u30b9\u00ae\u306a\u3069\uff09\u3092\u51e6\u65b9\u3055\u308c\u308b\u969b\u3001\u300c\u30ec\u30d0\u30df\u30d4\u30c9\uff08\u30e0\u30b3\u30b9\u30bf\u00ae\uff09\u300d\u304c\u4e00\u7dd2\u306b\u51e6\u65b9\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3088\u306d\uff1f\u81ea\u5206\u3082\u6295\u85ac\u306e\u969b\u306b\u306f\u300c\u75db\u307f\u6b62\u3081\u306f\u80c3\u3092\u8352\u3089\u3059\u3053\u3068\u304c\u3042\u308b\u306e\u3067\u3001\u80c3\u85ac\u3082\u4e00\u7dd2\u306b\u51e6\u65b9\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u300d\u306a [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":349,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"swell_btn_cv_data":"","footnotes":""},"categories":[3],"tags":[],"class_list":["post-343","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-3"],"_links":{"self":[{"href":"https:\/\/kurashinokusuribako.com\/index.php?rest_route=\/wp\/v2\/posts\/343","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kurashinokusuribako.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kurashinokusuribako.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kurashinokusuribako.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/kurashinokusuribako.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=343"}],"version-history":[{"count":3,"href":"https:\/\/kurashinokusuribako.com\/index.php?rest_route=\/wp\/v2\/posts\/343\/revisions"}],"predecessor-version":[{"id":350,"href":"https:\/\/kurashinokusuribako.com\/index.php?rest_route=\/wp\/v2\/posts\/343\/revisions\/350"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kurashinokusuribako.com\/index.php?rest_route=\/wp\/v2\/media\/349"}],"wp:attachment":[{"href":"https:\/\/kurashinokusuribako.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=343"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kurashinokusuribako.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=343"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kurashinokusuribako.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=343"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}